Orlistat (also known as tetrahydrolipstatin) is a drug
designed to treat obesity, and is sold in both prescription and
over-the-counter strengths.
Prescription orlistat is given to overweight people who may
also have high blood pressure, high cholesterol, diabetes or heart disease. It
is also often used after weight-loss to help people keep from gaining it back.
It works by preventing some of the fat in foods eaten from being absorbed by
the intestines. This un-absorbed fat then leaves the body in the stool.
Orlistat is usually taken three times a day with each main
meal that contains fat. Take it during a meal or up to 1 hour after. If you
miss a meal or if it does not contain fat, you can skip the dose. Do not take
more or less of it or take it more often than prescribed by your doctor. Taking
more will NOT block more fat!
If you are taking cyclosporine, take it 2 hours before or 2
hours after orlistat. Tell your doctor and pharmacist what medications you are
taking or going to take. Be sure to talk about any of the following:
anticoagulants; medications for diabetes, blood pressure, thyroid disease, and
other weight loss drugs.
Avoid Orlistat If
If you have had an organ transplant, if you have
cholestasis, or malabsorption syndrome, your doctor may tell you that orlistat
is not for you. Tell your doctor if you have or had an eating disorder, kidney
stones, diabetes, pancreatitis and gallbladder or thyroid disease. Do not take
orlistat if you are pregnant or breast-feeding.
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